Nazwa jednostki: Uniwersytet Jagielloński Collegium Medicum, Zakład Fizykochemicznej Analizy Leku
Nazwa stanowiska: Postdoctoral researcher
Link do strony www jednostki: https://farmacja.cm.uj.edu.pl/pl/jednostki/katedra-chemii-farmaceutycznej/zaklad-fizykochemicznej-analizy-leku/
Wymagania:
Requirements
Please note that the funding institution (National Science Centre) regulations apply: the degree must be obtained no earlier than 7 years before joining the project, but this may be extended by previous sick or rehabilitation leaves granted, a child care leave, in case of women by 18 months for every child born or adopted, whichever manner of accounting for career breaks is preferable. For details please refer to the following document: https://www.ncn.gov.pl/sites/default/files/pliki/koszty_edycja_33_en.pdf
Opis zadań:
The Post-Doc position is a vital part of a project Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer’s disease: development of dual inhibitors of GSK-3β and IKK-β kinases (total timespan 4 years, funding: nearly 2.5 milion PLN).
The project is an answer to the lack of effective treatment for Alzheimer’s disease (AD) and addresses a growing interest in the development of multifunctional ligands targeting the most relevant AD pathological processes. Recently, the search for disease-modifying therapies for AD has focused on tauopathy and neuroinflammation. GSK-3β is a kinase that is directly involved in these processes and its upregulation in AD leads to tau hyperphosphorylation resulting in dysfunction of axonal transport and increased inflammatory response. The inflammation process in neurons is mediated by NF-κB complex that plays a pivotal role in the immune response.
The successful candidate will be involved in:
Typ konkursu: Sonata Bis 9 – NZ
Termin składania podań: 20-09-2020 (godz. 23:59)
Forma składania podań: send your application to anna.wieckowska@uj.edu.pl (please put „PostDoc application” in the subject line). Based on applications, top candidates will be chosen for project interviews. These interviews will take place at the end of September 2020.
Warunki zatrudnienia:
The conditions of employment
Termin rozstrzygnięcia konkursu: 25-09-2020
Data rozpoczęcia pracy: 01-10-2020
Dodatkowe informacje:
Required documents
For additional information, please contact at anna.wieckowska@uj.edu.pl